3-({[(3S)-3,4-dihydroxybutyl]oxy}amino)-1H,2'H-2,3'-biindol-2'-one

This compound is an experimental small molecule belonging to the indole class of organic compounds. It is also known as Indirubin_E804 and has been studied primarily as a kinase inhibitor. Structural studies show it binds to and inhibits protein kinases, notably glycogen synthase kinase 3 beta (GSK3B), which plays a role in various cellular processes including metabolism and neurodegenerative disease pathways. The compound has been co-crystallized with calcium/calmodulin-dependent protein kinase from Cryptosporidium parvum, indicating its use in structural biology for probing kinase function[1][3][5]. Its primary mechanism of action is inhibition of serine/threonine-protein kinases.

Other names

Indirubin_E804